Navigating the Universe of Genetic Diversity

Home :: Technical Resources :: Material Safety Data Sheet :: Part 1 MATERIAL SAFETY DATA SHEET PART 1: What is the material and what do I need to know about it? PART I: What is the material and what do I need to know about it? 1. PRODUCT IDENTIFICATION 2. COMPOSITION AND INFORMATION ON INGREDIENTS 3. HAZARD IDENTIFICATION 1. PRODUCT IDENTIFICATION TRADE NAME AS LABELED: DMG DIVERSITY NAVIGATOR™ - EXONIC AMPLIFICATION AND SEQUENCING SYSTEM PART NUMBER: DMG-1A1-200, DMG-1A2-200, DMG-2A6-200, DMG-2B6-200, DMG-2C8-200, DMG-2C9-200, DMG-2C19-200, DMG-2D6-200, DMG-2E1-200, DMG-3A4-200, DMG-3A5-200, DMG-POR-200 MANUFACTURER: BioVentures, Inc. ADDRESS: P.O. BOX NUMBER 2561 MURFREESBORO, TN 37133-2561 EMERGENCY PHONE: 615 896-7353 DATE OF PREPARATION: JUNE 18, 2003 2. COMPOSITION AND INFORMATION ON INGREDIENTS Component 1: Amplification primer pairs, nested primer pairs and sequencing primers Chemical Name CAS# %v/v Exposure Limits In Air ACGIH OSHA OTHER TLV mg/m3 STEL mg/m3 PEL mg/m3 STEL mg/m3 IDLH mg/m3 Hydroxymethyl-aminomethane (Tris) 78-86-1 <1 NE NE NE NE NE NE Ethylenediamine-tetra-acetic acid (EDTA) 60-00-4 <1 NE NE NE NE NE NE Acetonitrile 75-05-8 2 NE NE NE NE NE NE Synthetic oligonucleotides NA <1 NE NE NE NE NE NE Water 7732-18-5 Balance NE NE NE NE NE NE NE = Not Established, NA = Not Applicable *All WHMIS required information is included in the appropriate sections based on ANSI Z400.1-1993 format Component 2: DNA control sample Chemical Name CAS# %v/v Exposure Limits In Air ACGIH OSHA OTHER TLV mg/m3 STEL mg/m3 PEL mg/m3 STEL mg/m3 IDLH mg/m3 Human genomic DNA NA <1 NE NE NE NE NE NE Hydroxymethyl-aminomethane (Tris) 78-86-1 <1 NE NE NE NE NE NE Ethylenediamine-tetra- acetic acid(EDTA) 60-00-4 <1 NE NE NE NE NE NE Polyoxyethylene sorbitate monolaurate (Tween-20) 9005-64-5 <1 NE NE NE NE NE NE Water 7732-18-5 Balance NE NE NE NE NE NE NE = Not Established, NA = Not Applicable Component 3: 5X PCR Buffer Chemical Name CAS# %v/v Exposure Limits In Air ACGIH OSHA OTHER TLV mg/m3 STEL mg/m3 PEL mg/m3 STEL mg/m3 IDLH mg/m3 Hydroxymethyl-Aminomethane (Tris) 78-86-1 <1 NE NE NE NE NE NE Potassium Chloride 7447-40-7 <2 NE NE NE NE NE NE Magnesium Chloride 7791-18-6 <1 NE NE NE NE NE NE Dimethyl Sulf- oxide (DMSO) 67-68-5 10 NE NE NE NE NE NE DL-Dithiothreitol (DTT) 3483-12-3 <1 NE NE NE NE NE NE Deoxyadenosine-5’-triphosphate 1927-31-7 <1 NE NE NE NE NE NE  Deoxycytidine-5’-triphosphate 102783-51-7 <1 NE NE NE NE NE NE Deoxyguanasine-5’-triphosphate 93919-41-6 <1 NE NE NE NE NE NE Deoxythymidine-5’-triphosphate 18423-43-3 <1 NE NE NE NE NE NE Water 7732-18-5 Balance NE NE NE NE NE NE NE = Not Established, NA = Not Applicable Component 4: 5X Sequencing Buffer Chemical Name CAS# %v/v Exposure Limits In Air ACGIH OSHA OTHER TLV mg/m3 STEL mg/m3 PEL mg/m3 STEL mg/m3 IDLH mg/m3 Hydroxymethyl-aminomethane (Tris) 78-86-1 <4 NE NE NE NE NE NE Magnesium Chloride 7791-18-6 <1 NE NE NE NE NE NE Water 7732-18-5 Balance NE NE NE NE NE NE NE = Not Established, NA = Not Applicable Component 5: BioMarker Extended DNA Marker Chemical Name CAS# %v/v Exposure Limits In Air ACGIH OSHA OTHER TLV mg/m3 STEL mg/m3 PEL mg/m3 STEL mg/m3 IDLH mg/m3 Synthetic ds DNA NA <1 NE NE NE NE NE NE Hydroxymethyl-aminomethane (Tris) 78-86-1 <1 NE NE NE NE NE NE Ethylenediamine-tetra- acetic acid(EDTA) 60-00-4 <1 NE NE NE NE NE NE Potassium Chloride 7447-40-7 <2 NE NE NE NE NE NE Sodium Azide 26628-22-8 .01 NE NE NE NE NE NE Water 7732-18-5 Balance NE NE NE NE NE NE NE = Not Established, NA = Not Applicable Component 6: BioTracker 6X Loading Dye Chemical Name CAS# %v/v Exposure Limits In Air ACGIH OSHA OTHER TLV mg/m3 STEL mg/m3 PEL mg/m3 STEL mg/m3 IDLH mg/m3 Glycerol 56-81-5 30 NE NE NE NE NE NE Bromophenol Blue(BPB) 115-39-9 .25 NE NE NE NE NE NE Lauryl Sulfate(SDS) 151-21-3 .75 NE NE NE NE NE NE Hydroxymethyl-aminomethane (Tris) 78-86-1 <1 NE NE NE NE NE NE Ethylenediamine-tetra- acetic acid(EDTA) 60-00-4 <1 NE NE NE NE NE NE Water 7732-18-5 Balance NE NE NE NE NE NE NE = Not Established, NA = Not Applicable 3. HAZARD IDENTIFICATION EMERGENCY OVERVIEW This product contains nineteen components which are clear, colorless solutions. The primary hazard associated with these solutions is irritation of contaminated eyes and skin or the generation of irritating vapors when solutions are heated. In the event of fire, this product will not contribute significant additional hazards. SYMPTOMS OF OVER-EXPOSURE BY ROUTE OF EXPOSURE: No adverse health effects should occur from routine use of this material in the manner specified by the manufacturer’s instructions. The only likely symptom of exposure would be reddening or inflammation after accidental injection. The potential health effects of the individual components are as described below: THE FOLLOWING INFORMATION DESCRIBES THE EXPECTED HEALTH HAZARDS ASSOCIATED WITH THE COMPONENT SOLUTIONS: BIOHAZARD The donors for the DNA control sample were tested for infectious agents and found to be negative. No testing methods, however, can offer complete assurance of the absence of infectious agents. Products of human origin, therefore, should be handled in a manner consistent with the possibility that an infectious agent may be present. INHALATION Inhalation of a vapor, mists, or dusts of this product may cause mild irritation. Symptoms are generally alleviated upon breathing fresh air. CONTACT WITH SKIN or EYES Contact with the skin or eyes may cause mild irritation, which is alleviated upon rinsing. SKIN ABSORPTION Avoid contact with Dimethyl Sulfoxide solutions containing toxic substances with unknown toxicological properties. Dimethyl Sulfoxide is readily absorbed through the skin and may carry such substances into the body. INGESTION Ingestion of the product’s components may cause gastric distress. INJECTION Injection of the product’s components may cause local reddening, tissue swelling, and discomfort. HEALTH EFFECTS OR RISKS FROM EXPOSURE: An Explanation in Lay Terms. These solutions are not known to cause significant acute or chronic health effects. Acute Beyond mild irritation of the skin or eyes, contact with this product does not usually cause acute health effects. Chronic This product is not known to cause any significant chronic health effects. Continue To Part 2	Our Products At BioVentures, we create our products to meet customer requirements with exacting standards, ensuring solutions that meet cost objectives as well as critical performance targets. ILLUMINATE™ GeneReleaser® MapMarker® BioMarker® BioTracker® DMG Diversity Navigator™ Bacterial Ribotyping Kit
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